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Standards, Health and Genetics in Dogs - Chapter II - Canine ophthalmology and genetics in dogs - Gilles Chaudieu (France) 1.0.0

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Abstract - Progressive selection has associated ocular conformation with breed morphotype. Some ocular lesions are linked to general morphological traits, whether normal or exaggerated.

The appearance of a mutation responsible for a monogenic inherited eye disease (IED) in a breed is called the founder effect, and may be ancient or recent. Most IEDs are passed on as simple autosomal recessive traits. Clinical diagnosis and knowledge of genealogy are required to suspect and confirm an ocular disease as an IED. Genetic testing must be used as a very informative complementary examination, which requires specific indications and has some limitations.

 


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