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Comparative analyses of genetic trends and prospects for selection against hip and elbow dysplasia in 15 UK dog breeds


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Authors: Thomas W Lewis, Sarah C Blott and John A Woolliams

 

excerpts from the abstract...

 

"This study aimed to both determine recent genetic trends in hip and elbow dysplasia, and evaluate the potential improvements in response to selection that publication of EBV for such diseases would provide, across a wide range of pure-bred dog breeds."

 

"EBV are shown to be both more accurate and abundant than phenotype, providing more reliable information on the genetic risk of disease for a greater proportion of the population. Because the accuracy ofselection is directly related to genetic progress, use of EBV can be expected to benefit selection for the improvement of canine health and welfare. Public availability of EBV for hip score for the fifteen breeds included inthis study will provide information on the genetic risk of disease in nearly a third of all dogs annually registered by the UK Kennel Club, with in excess of a quarter having an EBV for elbow score as well."

 

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    • The SKK - Svenka Kennelklubben (Swedish Kennel Club, in English), is Sweden's largest organisation dedicated to dogs and dog owners. We represent the interests of our 300,000 members – first time dog owners, experienced breeders, hunters, dog lovers, puppy buyers, exhibitors, agility competitors and many more.   Website: http://www.skk.se/en/ Database: Avelsdata Follow this link for the SKK Blog at DogWellNet Follow this link for more information on the Swedish Kennel Club including our organizational structure, code of ethics, and more.
    • A Continuing and Sustainable Development The International Partnership for Dogs (IPFD) and DogWellNet.com have come into being following a long history of efforts by many stakeholders to address dog health and well-being. An abbreviated timeline of key developments will highlight the complexity of issues addressed by the IPFD and DogWellNet and will list some of the many supporters and collaborators that have contributed directly or indirectly to this important work. Development was inaugurated under the patronage of the Fédération Cynologique Internationale (FCI). The major contributors (in-kind and funding) since 2011 have been, chronologically, the Agria Animal Insurance
    • IPFD has endorsed the Global Pet Obesity Initiative Position Statement, joining 24 International Veterinary Professional Organizations, including the American Veterinary Medical Association Board of Directors, British Small Animal Veterinary Association, Canadian Veterinary Medical Association, World Small Animal Veterinary Association, and others.
    • The Dog Breeding Reform Group (DBRG) is an organisation dedicated to improving the health and welfare of dogs through responsible breeding. It was founded in 2013 and became a Charitable Trust in 2015. Members of the DBRG include veterinary specialists, dog welfare and law experts, breeders and dog owners.
    • Neogen Genomics operations deliver innovative, affordable DNA testing for the discovery and commercial application of genomic advances that enhance the safety and abundance of life.   Neogen Genomics is a proud sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.            
    • Mars Veterinary is a business unit of Mars Petcare, the world’s largest pet care provider. Their mission is to facilitate responsible pet care by enhancing the well-being and relationship between pets, pet owners, breeders, shelters and veterinarians through valuable insights into pets as individuals.   Mars Veterinary is a proud sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.            
    • Raad van Beheer (The Dutch Kennel Club (DKC)) is the official kennel club of The Netherlands. Founded in 1902, it currently represents around 200 breed clubs with 150,000 members.   Raad van Beheer is a proud sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.      
    • The Veterinary Genetics Laboratory (VGL) at the University of California, Davis provides dog DNA testing services, including forensic genetic analyses, to a world-wide clientele. Validation and standardization of genetic tests across laboratories are areas in which the VGL has been engaged in for many years, primarily via workshops supported by the International Society for Animal Genetics.     The VGL is a proud sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.      
    • Sentinel Biomedical is a pioneering comparative health company committed to research and scientific innovation. The company’s primary focus is investigating canine cancers and identifying biological changes and environmental influences that may be shared with human cancers, making canines true watchdogs in the area of human health.   Sentinel Biomedical is a proud sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.      
    • Canine Medicine and Genetics is a peer-reviewed, open access journal addressing genetic, genomic and epidemiological research in both domestic and wild canids, relating to breed and species diversity, and canine evolution.  
    • Embark is more than a product, or even a company. It is a promise to share the journey of a lifetime with you and your dog. You invite us, via our app and website, into your home to help you understand and care for your dog like never before. We invite you to join us in making new discoveries in dog health, wellness, care, and understanding: via our research questions, regular results updates, blog posts, social media, and events.     Embark is a proud sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.      
    • Online Mendelian Inheritance in Animals (OMIA) is an online database, freely available to anyone in the world, created and curated in the Sydney School of Veterinary Science, within the University of Sydney, by Emeritus Professor Frank Nicholas, assisted by local and international colleagues.
    • Utilising the latest DNA technologies has enabled the VHLGenetics to grow exponentially since 1993.   Our experienced laboratories offer more than 1,000 routine DNA tests for animals, plants and microorganisms. The three locations offer the same DNA services, and the number of DNA tests available is routinely increased by the newest developments in the field.     VHLGenetics is a proud sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.          
    • Royal Canin is a global leader in pet health nutrition. In an industry that continues to adapt to popular trends in cat and dog food, our mission will remain the same; to constantly bring, through Health Nutrition and shared knowledge, the most precise nutritional solution for cats' and dogs' health nutrition needs, by building on constantly deepened scientific knowledge and Royal Canin's roots in the feline and canine professional networks.
    • CAG GmbH makes it easy to secure the genetic health of your four-legged friends. We provide the tools you need: a comprehensive offering of genetic tests, quick turn-around in the in-house accredited laboratory, and personal counseling to help you understand what the results really mean for you and your animal. With state-of-the-art technology, a robust R&D program, and dedicated specialists in animal genetics, CAG works with you to ensure the health and happiness of your best friend.     CAG GmbH is a proud sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.          
    • The Irish Kennel Club promotes the responsible ownership and breeding of dogs throughout Ireland through education, registration, training and support schemes and events.   Website: http://www.ikc.ie/ Irish Kennel Club Blog at DogWellNet: - under construction -
    • The Black Russian Terrier Club of America (BRTCA) is the AKC Parent Club for the Black Russian Terrier. BRTCA's mission is to do all in its power to protect and advance the interests of the breed and to encourage sportsmanlike competition at conformation shows, companion events and performance trials.    
    • Mission Facilitate collaboration and sharing of resources to enhance the health, well-being and welfare of pedigree dogs and all dogs worldwide. Vision An enduring global collaboration enhancing dog health, well-being and welfare, and human-dog interactions. Values Dog health, well-being and welfare and human-dog interactions contribute to the quality of life for both species. The world is a better place because we share it with dogs. Dog issues are important around the globe and international sharing and cooperation is needed. Goals The general goals of the IPFD are to:  Enhance the health, well-being and welfare of dogs and enri
    • The European School for Advanced Veterinary Studies (ESAVS) is a non for profit organization registered in Luxemburg dedicated to the advancement of veterinary medicine for companion animals. ESAVS was founded in 1991 as a project in the frame of the European Union‘s COMETT II and LEONARDO DA VINCI programs. It is affiliated with the Faculty of Science, Technology and Communication at the University of Luxembourg.  
    • Our laboratory provides a complete testing service for veterinary surgeons to meet the diagnostic needs of your practice.     LABOKLIN is a proud sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.      
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