Author:
Cathryn Mellersh, PhD
Animal Health Trust, Suffolk, UK
Presentation given at the 7th Tufts' Canine & Feline Breeding & Genetics Conference (2015)
2015 TUFTS PROCEEDINGS
The article can be accessed at:
excerpt...
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A DNA test gives information about the DNA sequence of an individual dog at a position in the genome that is known to influence a particular inherited trait.
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Most DNA tests are for a specific mutation that has been shown to cause an inherited disorder.
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Sometimes the mutation causes a 'cosmetic' trait, such as coat colour.
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Currently, most DNA tests are for mutations that cause 'Mendelian' or genetically simple inherited disorders.
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Increasingly DNA tests will become available for 'genetic risk factors,' which increase an individual's risk of developing a disorder but are not the 'whole story.'
Some good information for owners and breeders - considerations for using DNA tests to identify, manage or reduce heritable disease.
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